ABSTRACT
HSP70 is a kind of stress protein that takes care of protein through its life, and it has attracted attention as a factor to promote health. This protein is known for its induction route through hyperthermia stimulation. We compared differences between the effects of carbonic warm water bathing and tap warm water bathing, and the report obtained interesting results. The subjects are six healthy adults (average age: 23.8±5.5 years, each three from males and females), applied full immersion bathing at 41°C for 10min in both ca. 1, 000ppm of high concentration CO<sub>2</sub> warm water and tap warm water, and compared HSP70 before the bathing and one day after the bathing. During the observation of 24h, external thermal stimulation such as warm bathing was banned. 3 persons took warm bathing in CO<sub>2</sub> water first and the other 3 persons took tap water first. There was 10 days interval between the bathing in both types of bathing.<br>The results showed that an increase in precordial temperature measured with a deep-body thermometer was 1.0°C in tap warm water bathing and 2.3°C in CO<sub>2</sub> warm water bathing. The change in HSP70 was 3.31→4.35 (AU/mg protein: p=0.08) in tap warm water bathing and 3.42→5.04 (p<0.05) in CO<sub>2</sub> warm water bathing. Although a slight increase was recognized in tap warm water bathing, a significant increase in HSP70 was recognized in CO<sub>2</sub> warm water bathing.